All About Cialis

Cialis Overview

The latest innovation for erectile dysfunction, pill Cialis is in a class of medications known as PDE-5 inhibitors. Although Cialis , vardenafil and Viagra are different chemicals, they work in the same way. Manufactured by the Eli Lilly pharmaceutical company, Cialis meets the World Health Organization criteria standards and guidelines

Cialis Usage
Cialis is a tablet used to treat impotence. It can help men who suffer from erectile dysfunctions achieve and sustain an erection during intercourse.

How Cialis works
For impotence, Cialis works the same way as Viagra . It blocks an enzyme called phosphodiesterase-5, or PDE-5. It helps smooth the muscles in the penis to relax and widen, allowing for more blood to flow. As a result, erections are faster and easier with Cialis . Clinical trials suggest Cialis will take effect in less than 30 minutes following ingestion.

Cialis prescribed
Take Cialis approximately .50- 36 hours prior to sexual activity. A regular dosage is 20 mg once daily. (Erections are not automated by taking the Cialis pill alone -- without sexual arousal.)

Cialis IS NOT A:
  • Permanent cure for erectile dysfunction and impotence.
  • Safeguard against contracting sexually transmitted diseases, including HIV-the virus that causes AIDS.
  • Aphrodisiac or hormone.

    Cialis Side Effects
    Although there are a few adverse effects associated with Cialis , the most common ones are headache, myalgia (muscle pain), dyspepsia (upset stomach following meals) and back pain. The severities of these side effects are minimized with lower doses.

    Physician Checklist before beginning Cialis
    Only your doctor can decide if Cialis is right for you. Your doctor should determine if your heart is healthy enough to handle the endurance of having sex. Be sure to tell your doctor if you have had:
  • Any heart problems (e.g., angina, chest pain, heart failure, irregular heart beats, or heart attack), have ever had a stroke
  • Low or high blood pressure
  • A rare inherited eye disease called retinitis pigmentosa
  • Any kidney problems or any liver problems
  • Any blood problems, including sickle cell anemia or leukemia
  • Allergies to Sildenafil or any of the other ingredients of Generic Sildenafil Citrate tablets
  • A deformed penis, Peyronie's disease, or ever had an erection that lasted more than 4 hours

    Clinical Trials For Cialis
    In the clinical trial circuit, Cialis has made its debut. The Viagra competitor is being evaluated globally for its safety and staying power. The following case studies monitored the performance and health of 4000 men, in more than 60 studies.

    Clinical Trial_1
    The focal point of one clinical trial took 1,112 men with mild to severe erectile dysfunction. 804 were given Cialis . The other 308 were administered placebo. 81 percent of those treated with Cialis reported improved erections compared with 35 percent of those taking placebo. Test results showed that out of 700 participants at least 88% of men experienced improvement with their erections after using Cialis .

    Prevalent reported side effects were nasal congestion, headache, upset stomach, backache, muscle ache, dizziness, and flushing. However, the adverse effects reported with Cialis were brief, mild and moderate. As with other PDE5 inhibitors, the use of Cialis is contraindicated in patients who are taking nitrates. It should not be taken by patients with certain heart diseases for whom sexual activity itself is not advisable.

    Clinical Trial_2
    In another clinical trial by the Canadian Urological Association, the new data found the most common adverse side affects to be headache and upset stomach. This18-month study of 1,100 impotent men showed the side effects occurred in about 10 percent to 15 percent of patients. Of those, 6 percent stopped taking the drug due to side effects. The companies said any single side effect, such as headaches, accounted for less than 1 percent of discontinuations. Also the study of safety and tolerability in patients who were also taking medication for high blood pressure showed no increase in adverse symptoms.
    (Patients diagnosed with cardiac disorders were not included in the Cialis clinical trials. There is no conclusive data on the safety or efficacy of Cialis in cardiac patients.)

  • What are generic Cialis prescriptions?
    A generic Cialis prescription is the same as a Cialis brand name drug. The dosage, safety, and strength are the equivalent as Cialis brand name drugs. Generics differ in their packaging.

    Are generic Cialis drugs prescribed different from Cialis brand name drugs?
    No, generic Cialis drugs are prescribed for the same intended use as Cialis brand name drugs. The performance and quality are identical.

    Are Cialis generic drugs as safe as Cialis brand-name drugs?
    Yes. The Food and Drug Administration requires the safety and effectiveness in all drugs. Because generics are manufactured with the exact active ingredients, they work the same way in the body. (Generics have uniform risks and advantages as their brand-name counterparts.)

    Are Cialis generic drugs as effective as Cialis brand-name drugs?
    Yes, due to the strict guidelines of the FDA, Cialis generic drugs are required to have the same substance, quality, purity, and likeness as brand-name Cialis drugs.

    Do generic Cialis prescriptions take longer to work in the body?
    Yes, generic Cialis drugs perform precisely like brand-name Cialis drugs.

    Why are Cialis generic drugs less expensive?
    The primary reason generic Cialis are cheaper than brand name Cialis are in the way they are manufactured. Generics are not as costly to develop as a brand name and new drugs.
    New prescriptions are developed under patent protection. The patent protects the investment. The cost of manufacturing new Cialis drugs includes research, development, marketing, and promotion. Patenting allows the pharmaceutical company the sole right to sell the drug while it is in effect.
    Before patents reach expiration dates, manufacturers can apply to the FDA to sell Cialis generic versions. Because manufacturers do not have the same development expenditures, they can sell their product at substantially lowered prices. Moreover, once generic Cialis are approved, there is greater competition for the price to stay down. Currently, 48 percent of all prescriptions are filled with generic Cialis .

    Are brand-name Cialis made in more modern facilities than generic Cialis ?
    No. Both brand-name and generic Cialis facilities must meet the same criteria of good manufacturing practices. The FDA does not authorize drugs manufactured in substandard facilities. It conducts about 3,500 inspections a year to ensure standards are maintained.
    Generic firms have facilities comparable to those of brand-name firms. In fact, brand-name firms are linked to an estimated 50% of generic Cialis production. They frequently make copies of their own or other brand-name Cialis but sell them without the brand name.

    If brand-name Cialis and generic Cialis have the same active ingredients, why do they look different?
    In the United States, trademark laws do not allow a generic Cialis to look exactly like the brand-name Cialis . However, a generic Cialis must duplicate the active ingredient. Colors, flavors, and certain other inactive ingredients may be different.

    Does every brand-name Cialis have a generic counterpart?
    No. Customarily, brand-name Cialis are given patent protection for 20 years. However, when the patent expires, other drug companies can sell competitive generic versions; but only after thorough testing by the manufacturer and approval by the FDA.

    What is the approval process for generic Cialis ?
    Generic Cialis products are approved after the pharmaceutical company submits an abbreviated new drug application (ANDA). The Hatch-Waxman Act also referred to as the Drug Price Competition and Patent Term Restoration Act of 1984 made ANDA’s possible by creating a compromise in the drug industry. Generic Cialis companies gained greater access to the market for prescription Cialis , while innovator companies gained restoration of patent life of their products lost during FDA's approval process.